Long-time friends Vaughn (a devout hypochondriac) and Larry (a hapless, perpetually-single romantic) have never met a challenge from which they haven't run. When a chance encounter with a stranger leads to them being transported to an Old West town in the 1870s, they're forced into situations where failure seems the foregone conclusion. Terrified by change and even the hint of danger, Vaughn and Larry are given a task that must be completed within two weeks or they might never return to their modern-day reality. Given their built-in limitations, a hilarious series of events ensues as they work to overcome their fears and competing interests, and they must do battle with an ill-tempered gunslinger in an effort to return home.