Makeup artist Medy (Pokwang) was given the chance of a lifetime to accompany a concert star to the United States for a performance. She promised her family that she would return after a week. But while in America she stumbled upon former classmate Helen (Beth Tamayo), who convinced her to stay for good in the Land of Milk and Honey. She initially refused but eventually gave in, when she got a call one night from her husband that they needed a large amount of money to bring her youngest daughter to the hospital. America has not been the friendliest to her; the story begins with her coming home to Manila with virtually nothing. Medy's two kids, King (Rayver Cruz) and Queenie (Xyriel Manabat), are now 19 and 7. King struggles with his mother's return; animosity, resentment, shame, and anger are issues he has built with Medy. For young Queenie, it's getting to know the mother she thought would one day come out of a Balikbayan Box. As for her husband, Medy discovers something she least expected.